Porokeratosis Concurrent and Coexistent with Psoriasis Vulgaris

نویسندگان

  • Melissa M. Helm
  • Robert E. Kalb
چکیده

Disseminated superficial actinic porokeratosis is a rare photodistributed disorder that has occasionally been reported in association with psoriasis. Treatment of psoriasis with phototherapy may trigger the onset of porokeratosis in some cases. In other cases, the coexistence of these disorders may be coincidental. Clinical inspection of lesions of coexisting porokeratosis and psoriasis reveals increased erythema, diffuse and thickening of cornoid lamellae, as well as increased scale. These subtle yet characteristic features allow for correct clinical diagnosis and are associated with corollary histologic findings. Psoriatic changes occurring in lesions of porokeratosis are likely explained by the isomorphic (Koebner) response. Physicians should be aware that these two disorders can co-exist in order to ensure correct diagnosis and proper treatment. [N A J Med Sci. 2017;10(2):70-72. DOI: 10.7156/najms.2017.1002070]

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Coexistent skin lesions of vitiligo and psoriasis vulgaris. Immunohistochemical analyses for IL-17A-producing cells and regulatory T cells.

1http://www.medicaljournals.se/acta/content/?doi=10.2340/00015555-1713 Vitiligo vulgaris (VV) and psoriasis vulgaris (PV) are common dermatoses, with a worldwide occurrence of 0.5–1% and 1–3%, respectively. An imbalance between effector T cells and regulatory T cells (Tregs) can result in the pathogenesis of cutaneous immune diseases. In VV, interleukin (IL)-17-producing T-helper (Th) 17 cells ...

متن کامل

Disseminated Superficial Actinic Porokeratosis in a Patient with Psoriasis, after Long-Term Narrowband Ultraviolet B Phototherapy

Porokeratosis is a rare epidermal disorder characterized by annular or linear hyperkeratotic plaques with slightly raised thread-like borders, and in most cases, atrophic centers. Disseminated superficial porokeratosis and disseminated superficial actinic porokeratosis (DSAP), which primarily involve sun-exposed areas, are common types of porokeratoses. Histologically, a column of parakeratotic...

متن کامل

Giant Verrucous Psoriatic Plaque encircled by Porokeratosis: An Enigmatic Histopathological Association

Porokeratosis is an inherited, clonal disorder of epidermal keratinization classically characterized by development of single or multiple annular lesions with raised, sharply marginated, keratotic ridge and central atrophy. This clinical presentation may vary with different types of porokeratosis but histopathologically unified by the consistent finding of ‘cornoid lamella’. Porokeratosis may d...

متن کامل

Porokeratosis ptychotropica*

Porokeratosis is a skin disorder clinically characterized by annular plaques with keratotic borders resembling the Great Wall of China and histopathologically by cornoid lamellae. The disease has several clinical variants. Porokeratosis ptychotropica, which has recently become part of these variants, is quite rare and little known. The entity is characterized by verrucous plaques - which may re...

متن کامل

Porokeratosis ptychotropica: a rare manifestation with typical histological exam*

Porokeratosis is a disorder of epidermal keratinization characterized clinically by a distinctive ridge-like border, and histologically by cornoid lamellae. The known clinical variants of porokeratosis are: classic porokeratosis of Mibelli, disseminated superficial (actinic) porokeratosis (DSAP), porokeratosis palmaris et plantaris disseminata, linear porokeratosis and punctate porokeratosis. I...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2017